TNF alpha anticorps

N° du produit ABIN639286

Cet anticorps Souris détecte spécifiquement TNF alpha dans ELISA et FACS. Il présente une réactivité envers Boeuf (Vache).

Aperçu rapide pour TNF alpha anticorps (ABIN639286)

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivité: Boeuf (Vache)

Hôte: Souris

Conjugué: Cet anticorp TNF alpha est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Détail du produit anti-TNF alpha anticorps

Specificité: This product recognizes bovine TNF alpha, a 17.5kDa cytokine, expressed by many different stimulated cell types including monocytes, macrophages, endothelial cells, fibroblasts and both T and B-lymphocytes. The production of TNF alpha is induced by a variety of factors, dependant upon cell type and includes bacterial toxins, IL-1, PDGF, IFN-beta, NGF, Oncostatin M and viral infections. The presence of TNF alpha is responsible for diverse immunomodulatory, anti-tumour and toxic effects and under certain conditions is also capable of self-stimulation and inhibition.

Réactivité croisée: Mouton

Attributs du produit: Mouse Anti-Bovine Tumor Necrosis Factor alpha (TNF-alpha)

Purification: Purified

Immunogène: Recombinant bovine TNF alpha

Isotype: IgG2b

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur TNF alpha

Antigène: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Autre désignation: Tumor Necrosis Factor alpha (TNF-alpha)

Pathways: Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome